Pulmonology & Thoracic Oncology
Fleischner 2024 Nodule Criteria
Boostara evaluates solid, part-solid, and pure ground-glass nodules (GGN) per Fleischner Society 2024 and Lung-RADS v2022 guidelines. The AI calculates sub-voxel exponential Volume Doubling Time (VDT) across serial scans:
Where V₁ and V₂ are automated 3D spherical nodule volumes from serial low-dose CTs. A VDT of 30–400 days indicates malignant growth kinetics; benign granulomas typically exceed 600 days.
Kenya MOH TB Protocol Integration
In endemic African clinical regions, Boostara maps apical thick-walled cavitary lesions, tree-in-bud endobronchial spread patterns, calcified Ghon complexes, and bilateral upper lobe infiltrates — automatically generating sputum GeneXpert recommendation flags aligned with the Kenya National TB Programme guidelines.
Critical Alert: Tension Pneumothorax
Automated boundary mapping of the visceral pleural line with absent peripheral lung markings and contralateral mediastinal deviation triggers immediate chest decompression warnings within <350ms.
| Condition | AI Method | Guideline Reference | Performance |
|---|---|---|---|
| Pulmonary Nodule (SPN) | 3D Voxel Segmentation + VDT | Fleischner 2024 | 99.4% AUC 0.98 |
| Pulmonary Tuberculosis | Cavitary + Tree-in-bud Pattern | Kenya MOH NTLP | 97.8% |
| COVID-19 / Viral Pneumonia | Bilateral GGO + Peripheral Distribution | WHO Pneumonia Guidelines | 98.2% |
| Cardiomegaly & Pleural Effusion | CTR >0.5 Automated Measurement | ATS Clinical Standards | 99.1% |
| Tension Pneumothorax | Visceral Pleural Line Mapping | ATLS Emergency Protocol | <350ms Alert |
| Lung-RADS 1–4X Classification | Automated Nodule Risk Scoring | ACR Lung-RADS v2022 | 98.7% |
Loss Function — Ltotal = 0.6 × LDice + 0.4 × LFocal (penalises false negatives on sub-4mm nodules)